• Torment Difficulty:
Unique items can drop in Torment difficulty, with higher difficulties increasing your odds.
• Farm endgame boss:
Sanguivor, Blade of Zir can be target-farmed by defeating boss Lord Zir.
• Open World Drops:
Sanguivor, Blade of Zir can randomly drop from enemies, chests, and breakable objects.
• Helltide Chests:
Sanguivor, Blade of Zir can drop from chests during Helltide Events.
• Boss Farming:
Repeated Lord Zir runs are the best farming method if you specifically want Sanguivor, Blade of Zir.